Lab Medicine

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Incidence

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Medicine

65 Terms

1

Incidence

The number of NEW cases of a disease that develop in a population in a specific time period.

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2

Prevalence

Proportion of a particular population affected by a medical condition at a specific time.

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3

incidence

the number of new cases of diabetes in a new year would be called the

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4

Prevalence

The population living with diabetes would be the

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5

Sensitivity

The proportion of persons with disease in whom the test is positive.

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6

Specificity

The ability of a test to detect a disease in a true positive person

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7

Specificity

The proportion of persons without a disease that the test will be negative

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8

specificity

The chance that a test will be a true negative in individuals that do not have a disease

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9

TP / (TP+ TN)

Formula for sensitivity

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10

TN / (FP + TN)

Formula for specificity

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11

Positive predictive value

Percentage of patients with a positive test who truly have the disease

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12

PPV= TP / TP + FP

Forumula for PPV

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13

NPV = TN / TN + FN

Forumla for NPV

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14

Screening Test

Used to detect a potential health problem or disease that doesnt yet have signs or symptoms ( or that is early in development)

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15

Diagnostic Test

Test used to confirm diseases

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16

sensitivity

Screening test must have a high _____

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17

2

Reference range is within how many SD’s

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18

95%

2 SD’s account for what portion of a population

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19

Critical result flag

Results that are in the life threatening range. May be truly abnormal or the result of a problem with the sample

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20

Delta checks

Represents the difference between a patient’s current result and the previous result.

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21

hemoglobin

Main part of the red blood cell that carries oxygen

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22

Hematocrit

Ratio of the volume of erythrocytes to that of the whole blood

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23

Hematocrit, hemoglobin

____ , should be three times that of, ___

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24

hemoglobin

Hb stands for

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25

hematocrit

Hct stands for

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26

Hb

New borns have an elevated level of ____ (abbreviation)

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27

Hb

Females have lower levels of __ (ab) due to menses and lower testosterone

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28

Mean corpuscular volume

MCV stands for

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29

MCV

Mean volume of a RBC

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30

Macrocytic

Increased MCV is defined as

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31

Normocytic

Normal MCV is defined as

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32

microcytic

Decreased MCV is defined as

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33

Mean corpuscular hemoglobin

MCH stands for

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34

MCH

Contents of Hb in the average RBC

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35

Mean corpuscular Hemoglobin concentration

MCHC stands for

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36

MCHC

Average concentration of Hb in a given volume of packed RBC’s

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37

Red cell distribution width

RDW stands for

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38

RDW

Measures the RBC size variation

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39

increased

RDW is only signifiant if ______

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40

Iron def

A high RDW is associated with ____

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41

Hypochromic

Too little MCH/ MCHC

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42

Normal

If a RBC has a central pallor of 1/3 of diameter of cell, it is considered

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43

microcytosis

Low MCV is called

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44

Hypochromia

Low MCH is called

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45

Dilutional

Plasma volume can cause anemia due to what effect?

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46

Iron Def

Most common cause of microcytic anemia

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47

microcytic

Red blood cells are smaller than normal are called

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48

hypochromic

When greater than 1/3 of diameter is clear, it is called

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49

Hemolysis or bone marrow not working

Two causes of normocytic anemia

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50

retic count

Test used to see how well the body is responding to anemia

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51

Hemolysis

A high retic count greater than 3% suggest

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52

underproduction

Low retic count less than 3% suggest

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53

macrocytosis

If RBC’s lack central pallor, it is called

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54

chronic alcoholism

Macrocytes are associated with

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55

Megaloblastic anemia

Macrocytosis is associated with

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56

megaloblastic

b 12 or and or folic acid def is associated with

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57

Macrocytosis

The appearance of macro-ovalocytes is associated with

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58

Reticulocytes

Newly released erythrocytes that become mature RBC’s in 24 hours

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59

Reticulocytes

Detected in peripheral blood with supravital stain

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60

Reticulocytes

What does a supravital stain detect?

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61

increased RBC, Hb, HCT

Erythrocytosis is defined as

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62

erythrocytosis

Increased red cell mass due to increased production

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63

erythrocytosis

Chronic hypoxemia, blood doping and EPO from a tumor can all causes

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64

polychromatophilia

RBC’s that are even younger than reticulocytes

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65

[HCT/45] X retic count

Corrected retic count formula

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