Chapter 14: Forensic Toxicology

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Poison

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Poison

A substance that has a toxic (life threatening) effect on a person.

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Agonist

A drug that binds to a receptor and causes it to exert its function on the cell.

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Antagonist

Drugs that may bind to a receptor but not cause it to exert the action of the cell to which the receptor is attached.

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Clinical pharmacology

Which is concerned with the effects of drugs on humans.

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Drug Recognition Experts

Specially trained police officers that can administer a battery of field sobriety tests to a driver.

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Pharmacodynamics

Study of how drugs act in the body.

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Chemical tolerance

A phenomenon whereby the bodys organ systems adapt to the drug.

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Synergism

________ is easiest to detect if someone takes two drugs and has effects that would not be expected from either one of the drugs.

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Acetic Acid

Used by cells for energy and forms carbon dioxide and water.

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Forensic toxicologist

A scientist who works on cases where drugs are involved in death or injury.

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Henrys Law

States that when a volatile substance, such as alcohol, is dissolved in a liquid, such as blood, and then that liquid is brought in contact with a closed air space, such as alveolar breath, the ratio of the concentration of alcohol in the blood and breath is a constant at a given temperature.

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Drugs

A chemical or chemical mixture that is designed to have one or more physiological and /or psychological effects upon a person.

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Metabolism

A process whereby a drug or other substance is chemically changed to a different but related substance, called a(n) ________.

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Intoxilyzer

________ uses infrared spectroscopy for the measurement of alcohol.

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Alcohol

________ is also a CNS depressant, but its mechanism of action is different from barbiturates.

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urine samples

It is usually good scientific practice to use ________ to screen for the possible presence of a drug, but to use blood for determination of the concentration of the drug and for confirmation of its presence.

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Horizontal Gaze Nystagmus

The subject is asked to follow with his or her eyes only, a pencil or other object as the officer moves it slowly back and forth across the subjects field of vision.

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Withdrawal Syndrome

A well- defined set of physical symptoms, including high temperature, physical discomfort, pain, etc.

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Pharmacokinetics

________- concerned with how drugs move into and out of the body.

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Preliminary Breath Testing

Most of the PBTs work by either chemical oxidation or by fuel cell technology.

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forensic toxicologist

The ________ has a number of tasks that must be accomplished in order to reach conclusions about the role of a drug in causing death.

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Absorption

These include oral, intramuscular, intravenous, rectal, topical, subcutaneous, and inhalation

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Distribution

Blood reaches every cell in the body and drugs are distributed via the bloodstream.

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Elimination

through urine excretion; exhaled from lungs; by perspiration and respiration

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Screening

A type of preliminary test for drugs in body fluids

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Breath Alcohol Testing

most widely used method for alcohol testing in use today, especially given its near universal use in drunk-driving cases

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Drugged Driving

driving under the influence of drugs

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Drunk Driving

driving under the influence of alcohol

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Driving

_______ a car means that the subject is in the driver’s seat with the engine turned on and the car in motion on a road or other surface.

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Operating

______ a car means that the subject is in the driver’s seat and the engine is turned on but the car can be in the park—it doesn’t have to be in motion

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