Intro to Biotechnology: Applications of Biotech

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Biology

Biotech basics, history of biotech based on crash courses #40-#44, lab safety symbols, and NFPA diamonds

64 Terms

1

biotechnology

the study and manipulation of living things OR their component molecules, cells, tissues, organs, etc. to benefit human beings

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2

DNA fingerprinting

identifying the pattern of certain sequences in parts of DNA

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3

blue diamond

health hazard

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4

red diamond

fire hazard

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5

white diamond

specific harzard

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6

yellow diamond

reactivity hazard

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7

flammable

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8

oxidizing

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9

corrosive

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10

explosive

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11

general warning/harmful

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12

toxic

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13

gas

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14

health hazard

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15

environment

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16
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17

chromosomes

nucleus contained thread-shaped structures

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18

cell division

chromosomes played a critical role in this

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19

Linus Pauling

characterized the alpha helix structure of common proteins

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20

alpha helix

the structure of common proteins characterized by Linus Pauling

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21

James Watson and Francis Crick

what two scientists figured out DNA was a double helix?

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22

DNA

a machine language to make RNA, which became an assembly-language “program”

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23

Stanley Miller and Harold Urey

chemist and his advisor that produced amino acids

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24

amino acids

building blocks of life

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25

recombinant DNA (rDNA)

cloning sections of one organism’s DNA to another

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26

Diamond v. Chakrabarty

supreme court case that determined whether or not a company can patent a bioengineered life form; ruled in favor of respondent that it is legal

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27

chlorpromazine/thorazine

first blockbuster brain drug approved for psychiatric use; an anti-psychotic

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28

tranquilizers

first scientifically created, advertising-promoted drug for the “worried-well”

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29

valium

“mother’s little helpers”; many women took it due to the depression and anxiety may suffered from due to the loneliness and limitations the role of “housewife” that women had to follow back then

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30

chemical imbalance theory

theory that depression may be caused by elevating and lack of norepinephrine and serotonin

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31

cells grow indefinitely

what happens when one turns certain samples of human tissues into immortalized cell lines using tissue engineering?

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32

HeLa

most important cell line in biomedical research; particularly loaded technology; used to clone cells, revolutionized medicine, but the patient’s cell that was used never gave consent or received compensation

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33

genetically modified organism (GMO)

had its genome, or DNA blueprint, edited to include genes from another organism

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34

grains

big money GMOs, which first faced little pushback from consumers

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35

in-vitro fertilization

isolating gametes, or sex sells, and moving them around in labs

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36

somatic cell nuclear transfer (SCNT)

cloning

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37

sanger sequencing

chopping up DNA, tagging them to florescent dyes, and sorting out sequences by length

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38

Kary Mullis

developer of PCR

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39

polymerase chain reaction

developed by Kary Mullis; an automated way of taking advantage of natural processes for copying DNA

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40

Human Genome Project

began October 1st, 1990 & competed in 2003; had the goal of sequencing a representative “working draft” of 90% of a human genome—a model blueprint for the human body

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41

shotgun sequencing (shotgunning a genome)

fragmenting genome into bits in a row, then letting computers piece it back together to make the sequence

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42

BIll Clinton

who signed an executive order in 2000 to prevent genetic discrimination in federal workplaces

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43

DIY bio

movement where amateurs can sequence DNA and do bioengineering at home

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44

Human Genome Diversity Project

collect DNA samples from thousands of people to understand human diversity

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45

Moore’s Law

the # of electronic switches that people could squeeze onto one computer chip would double

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46

Steve Jobs and Steve Wozniak

two engineers committed to computing for play, not just always work

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47

Microsoft

founded by Bill Gates in 1975

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48

Defense Advanced Research Projects Agency (DARPA)

to protect citizens from soviet attacks if power lines were out or to pass information quickly

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49

pack-switching

used by ARPANET to send data in small, independent, broken-up parts that can each find their own fastest routes and be reassembled later

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50

Sir Tim Berners-Lee

invented world wide web in 1990; built the first web browser

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51

block chain

list of time-stamped records which are linked using cryptography and resistant to fraud

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52

cryptocurrency

kinds of money not backed by sovereign nations but by groups of co-invested strangers on the internet (ex: NFTs)

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53

biosociality

associating with each other based on shared molecules

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54

genetic therapies

replacing regions of DNA to give a rise to disease with doctor-designed therapeutic gene; genes get taken out, changed, and out back un

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55

personalized medicine

each patient will have care tailored to each individual genome

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56

transcriptomics

how regions of DNA are copied into little strands of DNA

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57

proteomics

how proteins fold together

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58

metabolomics

how energy moves around inside and out of cells

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59

CRISPR

most efficient way of gene-edting; when a virus enters the microbe’s cell, it is recognized as being on the list and an associated protein cuts up the virus; it reads for specific DNA sequences and only cuts these; instead of a step-by-step process it enables a whole solution to be programmed all at once

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60

reprogenetics

engineering babies

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61

microbiomics

genomics of microbes

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62

synpases

collection of neurons joined by little gaps called ______.

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63

connectome

dream database for many researchers; a total map of how neurons are linked

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64

zip code

better predictor of health than a genetic code

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