BIO Exam 3

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Action Potential

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1

Action Potential

Depolarization and depolarization of an excitable cell

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2

Mechanoreceptors

  • pressure ---> depolarization of the cell

  • Frequency of the action potential reflects the amount of pressure being applied

  • more pressure --> more frequent action potential

  • respond to movement and forces (touch, feel, hearing)

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3

Chemoreceptors

  • Molecule binds to protein receptor which leads to depolarization of cell

  • Means of detecting food

  • Smell (olfaction)

  • respond to chemical substances

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4

Thermoreceptors

Respond to heat

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5

Photoreceptors

  • respond to light

  • relaxation/contraction of the lens determines level of focus

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6

Lateral Inhibition

if a given neuron is activated then neighboring neurons can be inhibited which sharpen the edges (sharpens perception)

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Light

changes shape of retinal molecule g-protein coupled receptor is activated cell is hyper-polarized

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8

Opsins

most animals only have 3 (green, red, blue)

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9

Graded Potential

refers to membrane potential which can vary by amplitude

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10

Structure of Muscles

  • Muscles grouped together in a bundle which group together

  • Sarcomere --> Myofibril --> Muscle Fiber

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11

Muscle Fiber

  • Elongated cells and have many nuclei

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12

Motor Unit

  • Smallest functional unit of the nervous system

  • Each fiber is controlled by one motor neuron

  • Single motor neuron can control multiple muscle fibers

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13

Actin and Myosin Interaction

  • Myosin head binds to ATP which leads to detachment from actin

  • Myosin head catalyzes hydrolysis of ATP forming ADP and P

  • Myosin head binds to actin forming cross bridge

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14

Muscle Contraction

  • Action potential from the motor neuron leads to release of ACH and depolarization of muscle cell

  • Depolarization leads to release of Ca2+ and causes change in Ca2+

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15

Slow Twitch Muscle Fibers

Move more slowly and help the body moving longer

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16

Fast Twitch Muscles

Help you move faster but for shorter periods of time

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17

Hydrophilic Hormones

  • Do not cross lipid bilayer

  • Activate signal transduction pathways

  • Responses occur more quickly

  • Effects last hours and not long lasting

  • Receptors located on the outer cell membrane surface

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18

Hydrophobic

  • Cross lipid bilayer

  • Alter gene expression and produce protein

  • Response is slower

  • Effect can last days/months

  • Binds to intracellular hormone receptors in cytosol or cell nucleus

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19

Releasing Hormones

Are peptide hormones, produced in the hypothalamus

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20

Direct Hormones

Act directly on the non-endocrine tissues

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21

Positive Feedback

  • occurs to increase the change or output

  • results of a reaction is amplified to make it react more quickly (contractions in childbirth)

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22

Negative Feedback

  • Occurs to reduce or change output

  • Results of reaction is reduced to bring back system to stable state

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23

High Blood Sugar

  • Pancreas signaled ---> Insulin released

  • Muscle and liver take up glucose and store is as glycogen

  • Decrease in blood glucose

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24

Low Blood Sugar

  • Pancreas signaled ---> glucagon released

  • Muscle and liver break it down and release glycogen

  • Glucose released ---> increase in blood glucose

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25

Determination of where blood flows

smooth muscle relaxation and contraction determines where blood flows

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26

Bulk Flow

  • movement of substances through a vessel or tissue due to pressure differences

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27

Arteries

  • More oxygenated

  • Carry blood away from the heart

  • lower volume (10-15%)

  • Higher pressure

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28

Veins

  • Less oxygenated

  • carry blood towards the heart

  • higher volume (65-70%)

  • lower pressure

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29

Pressure in capillary beds

  • Pressure higher on the arterial side where unloading occurs

  • Pressure lower on the venous side where loading occurs

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30

Pathway of blood

  • Deoxy. blood enters from right atrium form the inferior and superior vena cava

  • Deoxy. blood passes through the right aortic valve and enters the right ventricle

  • Deoxy. blood is pumped in the pulmonary arteries and through the pulmonary valve

  • Oxy. blood returns from the lungs to the left atrium

  • Oxy. blood enters the left ventricle through the left aortic valve

  • Oxy. blood is pumped by the left ventricle through the aortic valve into the systemic circulation

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31

SA (sinoatrial) Node

pacemaker, generates an electrical signal that causes the heart atria to contract

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32

Sympathetic Nervous System

  • releases epinephrine and norepinephrine to speed up the heart rate

  • System controls the fight or flight response and prepares body for strenuous activity

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Parasympathetic Nervous System

  • releases acetylcholine to slow down the hear rate

  • System regulates functions, regulates during times of rest

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34

Pathways of Contraction in Atria and Ventricles

  • SA Node generates action potential that spread through the atria and contract in unison

  • Signals from the SA node reach the AV node which activates and fires

  • Action potentials are transmitted through a set of modified muscle fibers

  • The polarization spreads from the modified muscle fibers through the entire ventricle and contracts

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35

Rhythmic Action Potentials and Ion Channels

  • Acetylcholine binds to G-protein coupled receptor that triggers opening of K+ channels, hyper-polarizes and closes the Ca2+ channels ---> slowing of heart rate

  • NE binds to G-protein coupled receptor that triggers the opening of Ca2+ channels, depolarizes ---> increase in heart rate

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36

Nitrogenous Waste

Must be eliminated by renal organs

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37

Glomerulus

  • Filters blood

  • As blood enters each nephron it enters clusters of tiny blood cells (glomerulus)

  • Thin walls of glomerulus allow smaller molecules, wastes and fluids to pass into tubules

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38

Concentration Gradient in Kidney

  • Nephron generates and provides opportunity to control what is excreted

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Nephron

  • Unit is repeated over and over to make the final structure of the kidney

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40

Loop of Henle

  • primary function is the recovery of water and sodium chloride

  • Allows the production of urine that is more concentrated than blood which limits the amount of water needed for intake

  • Consists of the descending and ascending limbs

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41

Descending Limb

  • Permeable to water, liquid reaching the bend of the loop is reacher in salt and urea and does a passive transport of water

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42

Thick Ascending Limb

Liquid returns through the limb and sodium chloride diffuses out of the tubule into the surrounding tissue where the concentration is lower

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43

Thick Ascending Limb

the tubule wall can effect further removal of salt, even against the concentration gradient in an active transport process

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44

ADH

Peptide hormone, allows for reabsorption of water coming out kidney

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45

Hemoglobin

  • has 4 subunits (quaternary structure)

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46

CRH

  • can act as a neurotransmitter when released from neurons in the brain

  • can produce a sense of anxiety/fear in certain regions

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47

Surface Area of Digestion

increasing surface area allows for better access to breaking down food, for digestion and absorption

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48

Peristalsis

series of muscle contractions in the digestive tract

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49

Amalyase

found in saliva, breaks down starches, carbohydrates

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50

Lipase

breaks down lipids

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51

Pepsin

breaks proteins into amino acids

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52

Large Intestine

  • reabsorption of water, minerals, ions (Na & Cl)

  • Formation of storage and explusion of feces

  • Houses bacteria

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53

Hepatic Portal System

venous system that return blood from the digestive tract and the spleen to the liver

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54

Leptin

peptide hormone released by fat cells in proportion to adiposity, it is released in proportion to how much adipose tissue you have in your body

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55

Evaporation

great amount of heat is lost in transition of liquid to gas, lots of energy occurs

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56

Conduction

direct transfer of thermal motion between molecules of objects in direct contact, heat goes from higher to lower temp. object

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57

Radiation

electromagnetic waves of all objects, can transfer heat between two objects not in direct contact

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58

Convection

transfer of heat by movement of air or water

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59

Inhibitory Postsynaptic Potential

temporary hyper polarization of postsynaptic membrane caused by the flow of negatively charge ions into the postsynaptic cell , pushing away from the threshold

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60

Excitatory Postsynaptic Potential

synaptic inputs that depolarizes the postsynaptic cell, bringing the potential closer to threshold and closer to firing an action potential

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61

Cardiac Muscle

branched and striated, each fiber has a nucleus and at the end of intercalated discs

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62

Smooth Muscle tissue

not striated, smooth, one nucleus in each fiber, found in digestive system, arteries and veins, bladders

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