Acute Inflammation

________ contains substance capable of damaging and killing bacteria:

________) causes endothelial cell necrosis and detachment that affects blood vessels.

________ (chemokines) and cytokines affect adhesion and transmigration.

________ are converted from low- affinity to high- affinity forms by chemokines.

________: response of vascularized tissue that delivers leukocytes and molecules of host defense from the circulation to the sites of and cell damage in order to eliminate the offending agents.

________: purulent inflammatory exudate rich in neutrophils and cell debris.

After ________, P- selectin is rapidly translocated to the cell surface.

Increased ________ causes exudation of protein- rich fluid.

________: excess fluid in interstitial tissue or body cavities.

________ leading to an increase in blood flow.

________: neutrophils (6 to 24 hours), replaced by monocytes (24 to 48 hours)

________ (to eat and destroy): engulfment of foreign materials by phagocytic cells.

________: excess extravascular fluid with low protein content.

________: movement of leukocytes towards the site of inflammation.

________: inflammatory extravascular fluid with cellular debris and high protein concentration.

________= increased blood viscosity and increased concentration of red blood cells= stasis.

________: certain chemical substances and certain bacterial products that are able to attract leukocytes towards the site of inflammation.

________: expressed on platelets and endotheium.

A(n) ________ resulting from elevated fluid pressures or diminished plasma osmotic forces.

________: expressed on leukocytes.

neutrophils

lymphocytes

increased eosinophils

neutrophils (6 to 24 hours), replaced by monocytes (24 to 48 hours)

expressed on endothelium

histamine and thrombin

IL-1 and tumor necrosis factor (TNF)

intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1)

crawling of leukocytes between endothelial cells and squeezing along the intercellular junctions and through basement membrane into extracellular space

engulfment of foreign materials by phagocytic cells