Nutrition 2000 Exam 3

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What are the building blocks of protein?

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Emily Bourne- Spring 2023

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1

What are the building blocks of protein?

amino acids

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2

What are the different structures of protein?

-carbon atom with amine group and acid group attached

-disitive chemical side chain attached to the center carbon of the backbone

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3

What are the essential amino acids?

histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine

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4

What are the nonessential amino acids?

alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, proline, serine, tyrosine

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5

What is a conditionally essential amino acid?

nonessential amino acid can become an essential amino acid

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6

What are the conditionally essential amino acids?

tyrosine, cysteine, proline, arginine, glutamine

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7

What are the precursors of essential amino acids?

phenylalanine, methionine, serine, glutamate, glutamine, aspartate, ammonia

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8

What are the different protein structures?

primary, secondary, tertiary, quaternary

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9

What is the protein structure of hemoglobin?

quaternary structure

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10

What happens to the amino acid sequence of sickle-cell anemia?

instead on glutamic in the sequence it is replaced with valine

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11

How is protein digested?

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12

What are the different hormones involved in protein digestion?

secretin and cholecystokinin (CCK)

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13

What are the different enzymes used in protein digestion?

dipeptides, tripeptides, and amino acids

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14

What roles do proteins play in the body?

-regulation of gene expression

-provide structure and movement

-building enzymes

-building hormones

-neurotransmitters

-building antibodies

-transporting substances

-maintaining fluid and electrolyte balance

-maintaining acid-base balance

-provide energy and glucose

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15

What is the process of protein synthesis?

-occurs in the cytoplasm

-transcription (DNA→mRNA)

-translation (mRNA to ribosomes)

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16

What is protein turnover?

process of breakdown, recovery, and synthesis

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17

What is the DRI for protein for healthy adults

no more than 35% of diet

-0.8g/kg

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18

What happens in the body with an oversupply of amino acids?

-body removes and excretes amine groups

-uses the residues in three ways: meet immediate energy needs, make glucose for storage as glycogen, and make fat for energy storage

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19

What are some examples of positive nitrogen balance?

nitrogen-in exceeds nitrogen out

ex. growing child or pregnant women

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20

What are some examples of negative nitrogen balance?

nitrogen-out exceeds nitrogen-in

ex. muscle breakdown due to injury

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21

What is Marasmus?

wasting, emaciation

-chronic insufficiency of energy and protein

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22

What is Kwashiorkor?

-adequate energy with insufficient protein

-edema due to loss of blood protein

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23

What is the difference between Marasmus & Kwashiorkor?

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24

What is the BMI for someone who is underweight?

less than 18.5

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25

What is the BMI for someone who is overweight?

25-29.9

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26

What is the BMI for someone who is obese?

30-39.9

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27

What is the BMI for someone who is extreme obese?

over 40

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28

What are the different risks of being underweight?

first to die during a siege or famine, hospital stays, wasting disease, cancer

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29

What are adipokines?

hormones released by adipose tissue; helps regulate the inflammatory processes and energy metabolism in the tissues

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30

What are the major obesity-related chronic disease risk?

heart disease, stroke, high blood pressure, high cholesterol, type 2 diabetes, sleep apnea, liver and gallbladder disease

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31

What is the difference between visceral & subcutaneous fat?

visceral is stored within the central abdominal cavity

subcutaneous is fat between the skin

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32

What is body mass index(BMI)?

indicator of health risk from obesity or underweight

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33

What are the risks of having too much body fat?

obesity-related illnesses, chronic diseases, risk from extreme obesity equals the risk of death from smoking, inflammation

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34

What factors affect BMR(table 9.3)?

sum total of all involuntary activities necessary to sustain life, excluding digestion

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35

What are the different ways to measure body composition and fat distribution?

skin fold test, dual-energy X-ray absorptiometry, or waist circumference

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36

What is the hunger-stimulating hormone? Where is it secreted?

Ghrelin which is secreted in the stomach

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37

What is the appetite-suppressing hormone produced in the fat cells that conveys information about body fatness to the brain?

leptin; an adipokine hormone

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38

What are each of the energy yielding nutrients effect on satiety?

-protein has the greatest satiating effect during meal

-carbohydrates provide slowly digestible carbohydrate and soluble fiber, also contribute to satiation and satiety

-fat famous for triggering a hormone that contributes to long-term satiety, goes almost unnoticed by the appetite control system

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39

What are the “stop” and “go” signals?

-”go”: mechanisms that stimulate eating

-”stop”: mechanisms that supress eating

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40

What is the function of Ghrelin?

hunger-stimulating hormone

opposes weight loss

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41

What is the function of Leptin?

regulates frequency of meals

an adipokine hormone

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42

What happens during feasting?

-carbs→glucose→liver & muscle glycogen & body fat

-fat→fatty acids→body fat

-protein→amino acids→body fat & nitrogen lost in urine

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43

What happens during fasting?

-liver & muscle glycogen→glucose→energy

-body fat→fatty acids→energy

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44

What happens when the fast continues beyond glycogen depletion?

-body protein→amino acids→glucose, nitrogen, ketone bodies→energy

-body fat→fatty acids→ketone bodies→energy

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45

What is the body’s response to being energy deficit?

-gradual weight loss is preferred

-fasting

-ketosis

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46

What is the body’s response to energy surplus?

-protein breakdown

-fat broken down to glycerol and fatty acids

-carbohydrate broken down to sugars

-alcohol used for fuel or converted to fat for storage

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47

Anorexia nervosa

-intense fear of body fatness or of weight gain or strive to prevent weight gain although underweight

-cessation of menstruation, mood swings, depression, physical exhaustion, and sleep deprivation

-self starvation

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48

bulimia nervosa

-binge eating and purging or vomiting

-false perceptions of body weight or shape

-fluid electrolyte imbalances, infections, adversely affects dental health

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49

Sleeve gastrectomy

80% of the stomach is removed, leaving a tube-like structure; this greatly reduces the stomach’s capacity and its output of ghrelin

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50

Gastric bypass

surgeon constructs a small stomach pouch and creates an outlet directly to the lower small intestine

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51

Gastric banding

surgeon uses a gastric band to reduce the opening from the esophagus to the stomach. the size of the opening can be adjusted by inflating or deflating the band through a port located just under the skin.

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52

What is the leading cause and second leading cause of death in the U.S.?

  1. Heart disease

  2. Cancer

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53

What is thrombus?

a stationary clot: tissue death caused is called thrombosis

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54

What is embolus?

a clot broken loose

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55

What is embolism?

clot remains stuck in a narrow artery

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56

What is an aneurysm?

an artery is blocked, it may swell and burst

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57

What are the nonmodifiable risk factors for CVD?

-increasing age

-male gender

-family history

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58

What are the modifiable risk factors for CVD?

-High blood LDL cholesterol

-Low blood HDL cholesterol

-High blood triglyceride levels

-High Blood pressure

-diabetes

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59

What are harmful things that can come from diabetes?

-atherosclerosis

-impaired kidney, eye, and nerve function

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60

What is the second leading cause of disability and death in the U.S.?

Cancer

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61

What happens during plaque development?

Particles of LDL cholesterol become trapped in the blood vessel walls, and these become oxidized by abundant free radicals produced during inflammation.

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62

What does the development of atherosclerosis involve?

-plaque development

-blood clot formation

-hypertension

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63

What is metastasis?

tumor overwhelms the healthy tissue in which it developed or exports its cells through the bloodstream to other parts of the body to initiate other tumors

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64

What is metabolic syndrome?

any three or more of the:

-high fasting blood glucose

-hypertension

-Central obesity

-low blood high-density lipoprotein (HDL)

-High blood triglycerides

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65

What effect does atherosclerosis have on blood pressure?

causes hypertension

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66

What is atherosclerosis?

damage to the cells lining the arteries

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67

What are symptoms associated with diabetes?

-intense hunger

-frequent urination

-intense thirst

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