FNN 100 exam

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Oxidant

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Nutrition

1st

130 Terms

1

Oxidant

A compound which oxidizes other compounds

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Pro-Oxidant

A compound which promotes oxidization

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Anti-Oxidant

A compound which inhibits/reverses oxidization

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4

Radical

Any atom that contains one or more orbital electrons with unpaired spin states

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5

In-Vivo

"Within the living"-Biological studies that are done testing whole living organisms (could be animals, plants or humans)

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In-Vitro

"Within the glass"-Studies on microorganisms, cells or biological molecules usually use test tubes, Petri dishes etc.

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In-Vitro antioxidants (also dietary antioxidants)

Vitamin E, Vitamin C, Selenium, carotenoids

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Function of Radical species

Everything we do creates free radicals (eat, exercise, breath)

  • They potentially play beneficial roles in reactions to viruses and bacteria (minimal) -Generally, they are harmful and we need to counteract them by eating fruits and vegetables.

  • Attack polyunsaturated fatty acids in lipoproteins and cell membranes (interfering with cellular transport systems) -Damage cell proteins

  • Cause DNA mutations

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9

Vitamin C

Needs Vitamin D for absorption Water soluable Body maintains 22mg/kG of body weight (body pool is 1500mg)

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RDA/DRI for Vitamin C

Males = 90 mg Females = 75 mg Smokers + 35mg UL= 2000 mg

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Functions of Vitamin C

Preventing scurvy (<300 body pool) Collagen Production Enzyme cofactor for Fe and Cu Regenerates other antioxidants

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Food sources of Vitamin C

Citrus fruits and berries Tomatoes Brussel Sprouts and spinach Broccoli and cauliflower Potatoes

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Carotenoids Functions

Best biomarker for fruit and veg intake Pro vitamin-A activity

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Food sources of Carotenoids

Colourful fruits/veggies Papaya, melon, peaches Yam, squash, carrots peppers

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Functions of Vitamin E

Protects cell membrane Antioxidants for LD lipoprotein and lung cells

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Vitamin E excretion

Chylomicrons deliver Vitamin E to the liver -> forming part of Very low density Lipoprotein (cholesterol) and travels to tissues

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Deficiency of Vitamin E

Primary deficiency = rare (due to malabsorption, genetic mutations) hemolytic anemia (rbc degrade)

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Food sources of Vitamin E

In foods that contain fat vegetable oils meat, fish, poultry

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DRIs for Vitamin E

RDA: Men/women 19-50 yrs = 15 mg/day UL= 1000mg

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Functions of Selenium

14 selenoprotein production Vitamin C redox status Regulates thyroid hormone action

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Food sources of Selenium

Muscle meats and organs

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Deficiency of Selenium

Very rare, caused from areas where soil is low in selenium

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Selenelosis

Selenium Toxicity, causes brittle hair and nails, garlic breath

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DRIs for Selenium

RDA Males/females 19-50 yrs = 55 mcg/day UL= 400mcg

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Excess Vitamin C supplementation

Lead to hampered endurance capacity

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Excess Vitamin E supplementation

Immunity study → NO difference in race times, Supplementation PROMOTED lipid inflammation.

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Excess Vitamin C and E supplementation

Combined study PLACEBO group → MORE lean mass

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Function of Water

Delivers nutrients and removes waste Lubricant and cushion Chemical rxn medium Blood volume component Removes heat from body

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Body Water

~50-60% of the human body is water 3 g of water per 1 g glycogen

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Water and cells

65% is intracellular (within cells) 35% is extraacellular (outside cells)

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DRIs for Water

2.7 - 3.7 L

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Caveats of water DRIs

20% of this requirement can come from food All fluids count towards this requirement Assumes normal activity

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Alcohol

Class 1 carcinogen Associated with cancers

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Coffee and Water (study)

Studies show coffee consumption provided similar hydrating qualities to water

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Hyperthermia

Going above normal temperature (~37*C)

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Leading cause of death in athletes

Exertional heat stroke

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Electrolytes

Salts that dissolve in water in form of charged ions → can conduct electrical impulses

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DRIs for Sodium (Na)

AIs = 1200-1300mg/day UL = 2300 mg/day

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Hypernatremia

Increased plasma sodium concentration caused by water loss, gain in sodium (dietary or renal) or both (osmosis)

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Hyponatremia

A serum, plasma or blood sodium concentration below the normal reference range of the laboratory performing the test (<135 mmol)

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Food sources of Potassium

Best source: Sweet potato

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Hypokalemia

Potassium Deficiency

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Hyperkalemia

Very rarely dietary, most often seen with medical conditions (heart disease), prescription drugs, severe dehydration, renal disease, immunosuppressants, supplemental overdose

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Conduction

Heat transfered directly from one object to another

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Convection

Heat loss by passage of air/fluid over skin

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Radiation

Objects that are hotter than surroundings lose heat to surroundings

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Evaporation

Sweating (1L per hour)

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Dehydration

2% loss of body weight in a day Dark urine high plasma osmolality

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49

What is the best exercise?

Any exercise you are inclined to do and can stick to

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Recommendation for Exercise

150 minutes per week (minimum), strength training 2x a week

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Basic Principles of Exercise training (5)

Specificity, progressive overload, individuality, periodization, reversibility

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Progressive Overload

Slowly increasing the stress placed on a muscle or system in order to produce greater adaptation/improvement

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Specificity

The improvements gained from exercise training will be highly specific to the type of exercise undertaken.

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Individuality

Training should be modified to account for every individual's unique capacity for and response to training.

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Periodization

Varying some aspect of training (ie. frequency, intensity, type) over specific periods of time.

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Reversibility

The benefits obtained through training are rapidly lost once a person stops exercising

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Results of untrained people vs trained people

Untrained people will have greater results than one who is consistently exercising.

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Exercise and mortality rate

Exercising lowers mortality rate

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Functions of Iron

Transports O2 in blood Energy metabolism in citric acid cycle and ETC Involved in immune system DNA synthesis

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DRIs of Iron

8-18 mg (higher for females)

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Food sources of Iron

Organ meats, blood, muscle meat, soy (natto)

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Two types of Iron

"Heme" iron (animal flesh) "Non-heme" iron (plants)

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Iron Deficiency (factors which contribute)

Poor diet, genetics, periods, exercise induced hemolysis and hematuria

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Anemia

End stage of iron deficiency

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Good Hemoglobin Levels

115 g/L + (females) 135g/L + (males)

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Two forms of Vitamin A (found via diet)

Preformed Vitamin A (retinol) Provitamin A carotenoids

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Functions of Vitamin A

Vision Growth and reproduction Gene expression Immune function

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Food sources of Vitamin A

Preformed Vitamin A: Animal products (liver, milk and eggs) and other fortified foods Carotenoids: plant foods

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DRIs for Vitamin A

700-900 ug/day UL= 2000 ug/day

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Functions of Vitamin K

Blood clotting Coenzyme for protein synethsis that regulates plasma Ca and bone metabolism

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Food sources of Vitamin K

Intestinal microflora produce vitamin K (not enough to meet need) Liver, leafy greens, milk, cabbage

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DRIs for Vitamin K

AI: 90-120mcg/day

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Functions of Folate

Coenzyme in THF Homocysteine breakdown Blood volume and growth during pregnancy

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Function of Calcium

Bone Health Main component of bones

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DRIs for Calcium

RDA=1000mg/day UL= 2300 mg/day

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Function of Riboflavin

FAD and FMN metabolism Prevents abriflavinosis and cheilosis

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Food sources of RIboflavin

bread, fortified cereal organ meats, eggs broccoli

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Fallacies of Logic

naturalistic fallacy and false cause

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79

EAR

Estimated Average Requirement: Set for 50% of the population

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RDA

Recommended Dietary Allowance: Set for 97.5% of the population

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AI

Adequate Intake

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UL

Tolerable Upper Intake Level

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AMDR

Acceptable Macronutrient Distribution Range

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DRIs of Magnesium

RDA: 300-400 mg/day

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DRIs for Protein

RDA is 0.80 g per kg per day or 56 g/day for men

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86

RDA is 0.80 g per kg per day or 46 g/day for women

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DRIs for Niacin

RDA males (19+): 16 mg/day

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RDA females (19+): 14 mg/day

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DRIs for Vitamin D

600 IUs

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UL: 4,000 IUs

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DRIs for Folate

400 mcg/day

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RDA pregnancy: 600 mcg/day

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UL (19+): 1,000 mcg/day

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94

Kwashiorkor Disease

Protein Deficiency

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95

Affects children 2-5

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Resulting from recent severe food restriction, that is characterized by a swollen belly

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Marasmus

Protein Deficiency

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Affects infants 6-18 months old

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Due to chronic lack of energy intake where protein is used for energy

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100

Related to impaired brain development

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