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Addiction

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46 Terms
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Addiction

continued use of substances despite adverse consequences

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Abuse

use for purposes of intoxication or beyond intended use

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Withdrawal

symptoms occurring when substance no longer used

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4
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Tolerance

a gradual decrease in the action of a drug at a given dose in the blood

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5
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Alcohol

CNS depressant: mild sedation, coma, respiratory failure, death

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Wernicke encephalopathy

a degenerative brain disorder caused by thiamine deficiency. Characterized by vision impairment, ataxia, hypotension, confusion, and coma

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Korsakoff’s amnestic syndrome

a problem associated with alcoholism and is associated with impairment of understanding new information and retrieving memories

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Wernicke-Korsakoff syndrome

a memory disorder that results from a thiamine deficiency. Early symptoms can be reversed but if not, prognosis is poor

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Disulfiram

a medication that is used as a deterrent from drinking as it produces episodes of severe nausea and vomiting if alcohol is injested.

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Naltrexone

a medication used for treatment of alcohol and heroin abuse. reduces the craving for alcohol

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Alcohol withdrawal syndrome - Stage 1

increased HR, temperature, and slightly elevated BP. Slight diaphoresis, impaired appetite, hand tremors

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Alcohol withdrawal syndrome - Stage 2

high HR, BP, and temp. obvious diaphoresis, intermittent confusion, some visual and auditory hallucinations, painful anxiety and restlessness, tremors

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Alcohol withdrawal syndrome - Stage 3

Very high HR, BP, and temp. marked diaphoresis, disorientation/confusion, disturbing visual and auditory hallucinations, agitation, panic states, uncontrollable tremors, convulsions are common

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Cocaine class

CNS stimulant - increases dopamine, norepinephrine, and serotonin

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Cocaine effect

sudden burst of mental alertness and energy, feelings of self-confidence and being in control, sociability

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Withdrawal of cocaine

Severe anxiety, restlessness, and agitation

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long term use of cocaine

leads to depletion of norepinephrine leading to “crash” and sleeping 12 to 18 hours

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Amphetamine

block reuptake of norepinephrine and dopamine

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Methamphetamine

release of excess dopamine, highly addictive, used in a binge and crash pattern

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MDMA (ecstasy)

increased serotonin and excess dopamine release cause hallucinations, confusion, and sleep problems

possible malignant hyperthermia

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Nicotine

stimulation nervous systems to increase alertness, concentration, attention, and appetite suppression

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Nicotine withdrawal

mood changes, difficulty sleeping, h/a, increased appetitie

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Nicotine replacement therapy

used for withdrawal. Can use transdermal patches, nicotine gum, nasal spray, and inhalers

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Why do you withdrawal from nicotine earlier?

it has a shorter half life

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Caffeine

stimulates cerebral cortex, increase mental acuity

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Caffeine intoxication

nervousness, excitement, flushed face, diuresis, rambling flow of thought and speech, tachycardia

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Caffeine withdrawal

h/a, fatigue, difficulty concentrating, craving

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Cannabis (Marijuana)

binds with opioid receptors in the brain to block dopamine reuptake. Has a slow release because it is stored for weeks in fat tissue and int he brain

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Cannabis (Marijuana) side effects

impaired ability to form memories, recall events, and shift attention from one thing to another

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Hallucinogens effects

euphoria, altered body imagine, distorted visual and auditory perception, confusion

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Hallucinogens severe reaction

paranoia, fear of losing one’s mind, depersonalization, delusions

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Hallucinogens examples

Mushrooms, LSD, mescaline

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Opioid examples

oxycodone, hydrocodone, morphine, fentanyl, heroin

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Opioid withdrawal syndrome

rebound hyperexcitability

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Opioid reversal agent

Naloxone (Narcan)

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maintenance for opioid treatment

methadone therapy

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Inhalants

CNS depressants

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Inhalants effects

euphoria, sedation, emotional lability, and=4`1impaired judgement

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Inhalants intoxication

respiratory depression, stupor, and coma

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Using inhalants puts users at risk for

sudden sniffing death

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Steroids

cause increase irritability, aggression, euphoria, sexual arousal, mood swings

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Disulfiram (Antabuse)

used as a deterrent by causing severe nausea and vomiting if alcohol is consumed

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Naltrexone

helps to reduce cravings for alcohol and heroin

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Methadone

satisfies the craving of opioids but does not give the high of heroin

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Bupropion

an anti depressant shown to help people stop smoking

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Clonidine

a blood pressure med used in detox that helps with opioid withdrawal, specifically bone pain

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