Anatomy
study of form and structure
systemic approach
study one system (e.g. muscle, skeletal, etc.) at a time
regional approach
study one region at a time (e.g. shoulder or thigh) - includes bones, muscles, blood supply, nerves, etc.
Histology
study of tissues
microscopic
Anatomical position
feet facing forward
hands at sides with palms facing forward
body upright
head and neck facing forward
all descriptions of the body assume that the body is in the anatomical position, "standard orientation"
Sagittal
cuts body into left and right sections
movements in sagittal plane
flexion
extension
Hyperextension
midsagittal
cuts through the midline of the body
coronal (frontal) plane
cuts the body into front and back sections
movements in coronal plane
abduction/adduction
side flex ion
inversion/eversion
transverse (horizontal, cross section) plane
cuts transverse to the long axis of the structure
movements in transverse plane
medial/lateral rotation
horizontal abduction/adduction
protraction/retraction
pronation/supination
anterior
toward front
posterior
toward back
medial
towards midline
lateral
away from midline
superior
above
inferior
below
proximal
closer to body trunk
distal
distant from body trunk
superficial
closer to surface
deep
farther from surface
rostral
toward nose
caudal
toward tail
levels of classification
(small to big)
cells
Tissues
Organs
Organ system
Organism
epithelium functions
protection
sensory reception
Secretion/reception
Secretion/excretion (sweat)
Absorption
Ion transport
filtration (kidneys)
slippery surfaces for movement (lungs/heart and digestive organs
epithelial tissue
apical surface (faces free space/external environment like air/fluid)
basal surface (rests on basement membrane)
supported by connective tissue
avascular
highly innervated
highly regenerative (bottom level of cells will divide and regenerate)
cilia
many on a cell "beat" like a whip
no cytoplasm
move cells or substances (eg mucous) along cell surface
microvilli
finger like extensions that contain cytoplasm
increase surface area for absorption
glycocalyx
glycolipids and glycoproteins on cell surface
used for identification and communication
like how the body knows what cells belong to us (eg organ transplant)
simple squamous epithelium
single layer of flat cells looks like fried egg/pillow
simple squamous epithelium function
diffusion and filtration
simple squamous epithelium locations
alveoli of lung
glomerulus of kidney
endothelium (lines of blood vessels~~)~~
mesothelium (lines closed body cavities eg pleural cavity, pericardial cavity)
simple cuboidal epithelium
single layer of cube shaped cells (height = width)
simple cuboidal epithelium function
secretion and absorption
simple cuboidal epithelium locations
lines ducts and glands
kidney tubules
pancreatic ducts
simple columnar epithelium
single layer of column shaped cells (height>width)
may contain goblet cells (secrete mucous)
simple columnar epithelium function
secretion
absorption
ion transport
simple columnar epithelium locations
line much of the GI tract
lines some ducts
some cells are ciliated
pseudo stratified ciliated columnar epithelium
considered simple because all cells reach the basement membrane
has cilia
numerous goblet cells
looks stratified
pseudo stratified ciliated columnar epithelium location
lines upper respiratory tract, trachea, and larger bronchi
stratified squamous epithelium
23-30 layers of cells
apical layer of cells is flat (squamous)
basal layer is cuboidal
stratified squamous epithelium function
protection
stratified squamous epithelium locations
skin
esophagus
anus
vagina
transitional epithelium
considered stratified (5-7 layers thick)
top cells are dome shaped may be multi nuclear
transitional epithelium function
distends also protects
transitional epithelium locations
ureter
urinary bladder
urethra
stratified columnar/cuboidal epithelium
rare
in glands/ducts
protection
epithelial glands
exocrine and endocrine
can be unicellular (goblet cells)
multicellular
exocrine
secrete their substance in to a duct that empties "outside" the body
ie sweat, digestive enzymes
endocrine
secrete their substance into the blood
ie hormones into blood
connective tissue functions
supports: lies underneath epithelial tissues, provides blood supply and nutrients, pads and protects organs, absorbs shock
forms the basis of the skeleton (bone and cartilage)
surrounds blood vessels and nerves, binds tissue together
stores energy (adipose)
transports nutrients and other molecules (blood)
defends: helps the body fight against infection; major site for inflammatory responses
repairs damaged tissue, including scar tissue formation
connective tissue characteristics
few cells, lots of extracellular matrix
all connective tissue develops from embryonic mesenchyme
extracellular martix
ground substance + fibers
fibers = collagen, elastin, reticular
connective tissue cells
fibroblast
adipocytes
macrophages
mast cells
plasma cells
fibroblast
produce fibers and matrix
most abundant type of cell
looks like spindles or stars
adipocytes
store fat
macrophages
phagocytic to bateria, dirt, debris, dead tissue, etc
mast cells
release histamine, heparin, proteases
plasma cells
secrete antibodies
connective tissue fiber
collagen
reticular
elastic
collagen fibers
most abundant
strongest
reticular fibers
thin/delicate
made out of same protein as collagen fibers
allow more expansion than collagen
form mesh networks surrounding structures like capillaries
elastic fibers
expand and snap back into their original shape
connective tissue - ground substance
holds fluid
varies in form
blood = liquid
cartilage = gel like
bone = ossified, hard
types of connective tissue
loose connective tissue
dense connective tissue
special types of connective tissue
loose connective tissue
fewer fibers, more ground substance
areolar loose connective tissue
adipose
reticular connective tissue
dense connective tissue
more fibers, less ground substance
dense regular connective tissue
dense irregular connective tissue
elastic connective tissue
areolar loos connective tissue
most abundant connective tissue
areolar connective tissue locations
surrounds blood vessels, nerves
underneath epithelia (serous membranes)
in mesentery of abdomen
areolar connective tissue function
supports and binds function
holds body fluids
defends against infection
stores nutrients as fat
contains all fiber types
allows movement
adipose
large vascular supply
adipose function
energy storage
padding
shock absorption
adipose location
hypodermis
surrounds kidney an eye
found in mesenteries in the abdominal cavity
reticular connective tissue
contains only reticular fibers in its matrix
reticular connective tissue function
loosely filters fluid
acting as a screen to trap bacteria and foreign particles
reticular connective tissue locations
bone marrow
spleen
lymph nodes
dense regular connective tissue
lots of collagen fibers
parallel to the direction of tension
fibroblasts fill in the space between collagen fibers
not as much ground substance
dense regular connective tissue function
resits force in one direction
dense regular connective tissue locations
tendons and ligaments
deep fascia
dense irregular connective tissue
lots of collagen fibers in many directions
dense irregular connective tissue function
resists forces in many directions
dense irregular connective tissue location
dermis of skin
capsule around some organs
surrounds bone
elastic connective tissue
contains more elastic fibers than collagen fibers
elastic connective tissue function
allows recoil of tissue
elastic connective tissue location
walls of large arteries (eg aorta)
specific ligaments (ligamentum niche, ligamentum, flava)
brachial tubes in the lungs
muscle tissue functions
movement: skeletal muscle moves bone; move substance through an organ
maintenance of posture (resist gravity)
joint stabilization
heat generation (shivering)
develops from embryonic mesenchyme (like CT)
muscle tissue characteristics
contractility
excitability
extensibility
elasticity
contractility
muscle contracts forcefully
excitability
cells carry an electrical impulse
extensibility
muscle can be stretched
elasticity
after being stretched, muscle tissue can recoil passive and resume its resting length
type of muscle tissue
skeletal
cardiac
smooth
skeletal muscle tissue
striated: due to the pattern of actin and myosin
voluntary: under conscious control
multinucleated
blood supply: good
ability to grow and repair: some
cardiac muscle tissue
striated
involuntary: but cognitive thoughts and emotions can influence heart rate
has intercalated discs
blood supply: best (first in line for oxygenation)
ability to grow and repair: poor
gap junction
quickly spread excitation
allowing fast contractions
desmosomes
evenly spread force between cardiac muscle cells
smooth muscle tissue
unstriated - different organization of actin and myosin
involuntary contraction - slow and rhythmic
smaller, fusiform shaped cells with central nucleus
lines hollow organs
blood supply: least
ability to grow and repair: easily
nerve tissue function
receives sensory information
integrates and processes sensory information
initiates a response
summarized in a basic reflex arc
nerve tissue characteristics
high metabolic rate: needs a lot of oxygen and glucose
"soft" tissue: prone to injury
repair and healing depends on type of damage and location