biology- B2 organisation

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enzymes in mouth

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1

enzymes in mouth

amylase digests starch into smaller sugar molecules

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2

what does the stomach contain

hydrochloric acid, helps enzymes to start digestion of protein

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3

what does churning action in stomach do

turns the food into a fluid increasing the surface area for enzymes to digest

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4

chemicals released in to ... from ...

small intestine from liver and pancreas

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5

pancreas releases

enzymes continuing digestion of starch and protein, starts digestion of lipids

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6

liver releases

bile neutralises acid released from stomach, as it is an alkaline solution, speeding up digestion of lipids by lipase

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7

walls of small intestine release

enzymes continuing digestion of protein and lipids

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8

small intestine, absorption

small food molecules broken down by digestion are absorbed into bloodstream through active transport or diffusion

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9

large intestine

water absorbed into bloodstream

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10

rectum

short tube at end of the large intestine, waste material is compressed into a solid form

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11

anus

muscular opening at the end of the rectum, waste material is eliminated from the body

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12

what are products of digestion used for

build new carbohydrates, lipids and proteins

some glucose is used in respiration

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13

mouth enzymes

starch broken down by salivary amylase, produced by salivary glands, into maltose

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14

starch is broken down by...into...

amylase into maltose

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15

amylase is made in

salivary glands, pancreas, small intestine

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16

proteins are broken down by...into...

protease into amino acids

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17

protease is made in

stomach (pepsin), pancreas and small intestine

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18

lipids are broken down by...into...

lipase into glycerol and fatty acids

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19

lipase is made in

pancreas and small intestine

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20

bile

emulsifies lipids into smaller droplets, massively increasing surface area of lipid droplets, increasing rate of lipid breakdown by lipase

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21

at optimum pH or temp, enzymes have

max frequency of successful collisions between substrate and active site

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22

test for starch

iodine solution -positive- blue black -negative- orange yellow

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23

test for sugar glucose

benedict's solution, 5 min hot water bath green- small amount yellow- more brick red- lot

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24

drawback of benedict solution

doesn't work on non-reducing sugars, e.g. sucrose

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25

test for protein

buriet solution -positive- purple ring between layers -negative- no change

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26

test for fats/lipids

sudan II, shake positive- red layer forms

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27

test effect of pH on enzyme starch

  1. one drop of iodine solution in spotting tile

  2. 3 test tubes, each containing same volume of starch solution, amylase solution, pH 5 solution buffer solution (used to control pH)

  3. place 3 test tubes in water bath at 30 degrees C and leave for 10 mins to allow solutions to reach right temp

  4. combine 3 solutions, mix using stirring rod

  5. immediately return test tube to water bath and start stopwatch

  6. after 30s, use stirring rod to transfer one drop of solution to spotting tile

  7. iodine turns blue black showing starch is present

  8. take sample every 30s until sample remains orange, telling us starch is no longer present and reaction is finished

  9. stop stopwatch, record time taken

  10. repeat experiment many times, using different pH buffers, e.g. 6,7,8

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28

problems with effect of pH on enzyme amylase experiment

  1. only taking samples every 30s means time recorded for reaction to take place is approximate. instead take samples every 10 seconds

  2. looking for when iodine doesn't go blue black, not always obvious as colour change is gradual, hard to see when reaction finished. instead ask several people to look at spotting tile to decide when investigation is finished

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29

small intestine adaptation

very long, 5m in an adult human, very large SA

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30

small intestine interior is covered with millions of

millions of villi- massive increase SA

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31

adaptation of villi

covered with microvilli further increase SA

very good blood supply, increase concentration gradient

villi have very thin membrame, short diffusion path

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32

explain circulation in fish

single circulatory system-

deoxygenated blood goes from heart, to gills, where it gains oxygen, and then oxygenated blood passes straight to organs, oxygen diffuses out of blood into body cells, blood returns to heart

problem- blood loses pressure, as it passes through gills before reaching organs, blood can't travel as quickly to organs, meaning not as much oxygen is delivered

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33

explain circulation in humans

double circulatory system-

deoxygenated blood enters right and left atrium of heart through vena cava, atriums contract forcing blood into ventricles, ventricles contract forcing blood out of heart, blood is pumped from heart to lungs through pulmonary artery, blood gains oxygen in lungs, oxygenated blood returns to heart through pulmonary vein, and then leaves the heart through the aorta and is transported to organs, diffusing oxygen from blood to body cells, then the deoxygenated blood re-enters the heart through the vena cava

benefit- blood passes through heart twice, pressure is not lost, travel rapidly to body cells delivering more oxygen

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34

valves

between atrium and ventricles, prevent backflow of blood

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35

left side of heart is

thicker muscular wall, left side pumps heart all around body where as right side only pumps to lungs

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36

arteries

withstand high pressure from carrying blood, thick muscular walls

blood travels through in surges when heart beats, so elastic fibres stretch

in between surges, elastic fibres recoil, keeping blood moving

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37

capillaries

allows substances, like glucose and oxygen to diffuse from blood into body cells. carbon dioxide diffuses from body cells to blood.

very thin wall- shorter diffusion path

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38

veins

valves have very thin walls, carry low pressure blood

contain valves which prevent back flow of blood. when blood is flowing in the correct direction valves are open, when blood starts to flow backwards, valves close

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39

what four things is blood made up of

plasma, red blood cells, white blood cells, platelets

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40

plasma

liquid part of blood

transports:

  • soluble digestion products, e.g. glucose, from small intestine to other organs

  • carbon dioxide, from body cells to lungs, to be breathed out

  • waste product urea from liver to kidneys, to be excreted in urine

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41

red blood cells

transport oxygen from lungs to body cell

adaptations:

  • haemoglobin, combines with oxygen to form oxyhaemoglobin, which is released in organs (oxygen released)

  • no nucleus, more space to carry haemoglobin

  • biconcave shape, greater SA, oxygen diffuses in and out rapidly

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42

white blood cells

part of the immune system

adaptations:

  • nucleus containing DNA encoding instructions on how to do job

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43

platelets

tiny fragments of cells, helps= blood clotting

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44

why is blood clotting important?

it prevents excessive blood loss and the entry of microorganisms

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45

uses of donated blood

replace lost blood, platelets to help clotting, proteins extracted useful in antibodies

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46

lack of platelets leads to

excessive bleeding and brusing

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47

problems of donated blood

blood transfusions- must have same blood type or it will be rejected from immune system and patient may die

lots of diseases can be transmitted, but in UK, blood is screened for infections so risk is very low

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48

coronary arteries

branch from the aorta, and carry oxygen-rich blood to the heart muscle, oxygen is used in respiration, providing energy for contraction

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49

drug treatment of coronary artery disease

statins- reduce cholesterol in blood, slows down rate that fatty material builds in coronary artery

they are effective, but can cause liver problems

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50

physical treatment of coronary artery disease

stent- tube used to keep coronary arteries open

blood can flow normally, but won't prevent other areas of coronary arteries flowing, and won't treat underlying causes

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51

faulty valves can happen because

they do not fully open, heart has to pump extra hard to get the blood through, causing heart to enlarge

leaky valves causes patient to feel weak and tired0

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52

treatment for faulty valves

mechanical valve- last a life time, but increase risk of blood clots, patient take anti-clotting drugs

valve from animal- don't last as long, patients don't have to take drugs

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53

heart failure

heart of patients with cardiovascular diseases cannot pump enough blood around the body

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54

heart failure treatment

donated heart and/or lungs

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55

problems with heart donation

not enough hearts available to treat every patient, patient must take drugs to stop donated heart being rejected by immune system

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56

temporary heart failure treatment

artificial heart, while waiting for a heart transplant, or allowing damaged heart to rest

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57

downsides of artificial heart

increase risk of blood clotting, not a permanent solution as can only be used for relatively short amount of time

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58

air passes into lungs through

trachea

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59

trachea has

cartilage rings preventing it from collapsing when we inhale

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60

in the alveoli, oxygen diffuses

in to blood stream

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61

In the alveoli, carbon dioxide diffuses

out of the blood and into the air

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62

alveoli has

very thin walls, meaning diffusion path is very short

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63

alveoli have a

very good blood supply, meaning once oxygen diffuses in to blood it is rapidly removed, meaning concentration gradient is very steep

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64

alveoli has a large surface area because

there are millions of tiny alveoli

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65

breathing increases

rate of diffusion, as it brings fresh oxygen into alveoli and takes away carbon dioxide, meaning the concentration gradient is high

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66

benign tumours are

contained within a membrane

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67

malignant tumours...

invade neighbouring tissue and move into bloodstream, forming secondary tumours

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68

increased risk of lung cancer is caused by

radon- radioactive gas, it releases ionising radiation which damages DNA in cells, causing uncontrolled cell division, leading to cancer

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69

what is TB

communicable lung disease

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70

health

state of physical and mental well-being

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71

when is TB fatal

when someone has a weak immune system, e.g. someone with HIV

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72

someone with a weak immune system is more likely to

suffer from infectious diseases

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73

HPV is usually

essentially harmless

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74

an example of one disease being the cause of another is

HPV causing cervical cancer in some people

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75

disease triggered by immune system

allergies, e.g athsma or dermatitis

body is infected with pathogen, which immune system fights off, but person is left with allergy

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76

an example of mental illness triggering physical illness

arthritis leading to depression

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77

epideiology

scientific study of the patterns of disease to determine risk factors

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78

correlation does not

prove cause, but suggests they may be linked

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79

what in cigarettes causes damage to DNA and increases risk of cancer

chemical called carcinogens

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80

causal mechanism

something that explains how one factor influences another

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81

to avoid bias, sample must be

as large and random as possible

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82

why can't we draw conclusion about entire population from a small and non-random sample

a place may be exposed to more/less radiation, or the people may get more/less exercise

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83

high fat low veg diet leads to

increase of cholesterol levels in blood, increasing rate if fatty acid build up in artery, increasing risk of cardiovascular diseases

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84

high salt diet leads to

increase in blood pressure, increasing risk of cardiovascular diseases

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85

exercise lowers risk of

cardiovascular diseases

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86

smoking when pregnant

increases risk of miscarriage, premature birth, low body mass of baby

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87

drinking when pregnant

increases risk of fetal alcohol syndrome, leading to learning difficulties, and other mental and physical problems

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88

alcohol affects on brain

addiction and memory loss

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89

type 2 diabetes can lead to

blindness or amputation of a limb

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90

epidermal cells

form epidermal tissue, protects surface of leaf

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91

upper epidermis

transparent so light can pass through it to reach the photosynthetic cells. covered with waxy cuticle, which reduces evaporation from surface of leaf, prevents leaf from drying out

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92

lower epidermis

stomata- allows carbon dioxide to enter leaf and oxygen to leave. also controls water vapour that passes out of leaf. controlled by guard cells

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93

pallisade mesophyll

palisade cells equipped with lots of chloroplasts which contain chlorophyll to absorb sunlight for photosynthesis

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94

spongy mesophyll

full of air space, allowing carbon dioxide to diffuse through spongy mesophyll to palisade cells. oxygen diffuses the other way

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95

magnesium use in plants

making chlorophyll

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96

translocation

movement of sugars and other molecules through phloem tissue

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97

transpitation

water constantly evaporated from surface of leaves

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98

transpiration

water loss (vapor) through stomata open for gas exchange

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99

factors affecting transpiration

faster when - higher temp

  • dry conditions because this is when evaporation works faster

  • windy because wind removes any water vapour allowing for quicker evaporation

  • high light intensity because this increases rate of photosynthesis, so stomata open allowing carbon dioxide enter, so water vapour can pass out of leaf

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100

when light intensity is high

guard cells swell and change their shape, causes stomata to open. now co² can diffuse into leaf and be used in photosynthesis

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